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Non-invasive Evaluation of Portal Pressure Based on Biofluid Mechanics (PPBFM)

Non-invasive Evaluation of Portal Pressure Based on Biofluid Mechanics (PPBFM)

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DDD-17012940
Enrollment
Unknown
Registered
2017-10-11
Start date
2017-10-01
Completion date
Unknown
Last updated
2017-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirrhosis and Portal Hypertension

Interventions

Gold Standard:Hepatic Venous Pressure Gradient

Sponsors

Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University, School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Be at least 18 years of age; 2. Patients with cirrhosis or portal hypertension, scheduled for invasive HVPG measurement; 3. Be conscious and able to comply with study procedures; 4. Have read and signed the informed consent forms for participating in the study.

Exclusion criteria

Exclusion criteria: 1. Female patients who are pregnant or nursing; 2. Patients currently on chemotherapy or with other primary cancers requiring systemic or hepatic loco-regional treatment; 3. Patients who are medically unstable, terminally or seriously ill, or patients whose clinical course is unpredictable; 4. Patients with clinically unstable cardiac disease, for example: congenital heart defect, arrhythmia, uncontrolled heart failure (NYHA Class IV); 5. Patients with respiratory distress syndrome or clinically unstable pulmonary disease, for example: pulmonary hypertension, pulmonary emboli, pulmonary vasculitis, emphysema; 6. Patients with severe liver failure or hepatic encephalopathy (grade III-IV); 7. Patients with severe kidney failure; 8. Patients with severe coagulation disorders; 9. Patients with recent cerebral hemorrhage; 10. Patients with unstable occlusive disease or thrombosis within the hepatic, portal, or mesenteric veins; 11. Patients who are anaphylactic allergy to iodinated contrast.

Design outcomes

Primary

MeasureTime frame
Non-invasive Portal Pressure;HVPG;

Countries

China

Contacts

Public ContactLuo Meng

Shanghai Ninth People's Hospital affiliated to Shanghai Jiao Tong University, School of Medicine

luosh9hospital@sina.com+86 13817882266

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026