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Change in left ventricular global longitudinal peak strain values for early diagnosis of high-risk coronary atherosclerotic heart disease in elderly patients: study protocol for a single-center diagnostic trial

Change in left ventricular global longitudinal peak strain values for early diagnosis of high-risk coronary atherosclerotic heart disease in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DDD-17012839
Enrollment
Unknown
Registered
2017-09-29
Start date
2017-11-01
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early diagnosis of high-risk coronary atherosclerotic heart disease in elderly patients

Interventions

Gold Standard:The diagnostic gold standard of high-risk coronary atherosclerotic heart disease in elderly patients is = 50% diameter stenosis of left main coronary artery or = 70% diameter stenosis i
Index test:LVGLPS values

Sponsors

Taihe Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Chest pain as the first symptom; 2. Aged 60-80 years male and female; 3. Regular sinus rhythm; 4. No abnormal ventricular wall motion as confirmed by conventional echocardiography; 5. Provision of signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Myocardial infarction; 2. Heart valve disease; 3. Congenital heart disease; 4. Cardiomyopathy; 5. Use of pacemaker; 6. Chronic obstructive pulmonary disease and liver and kidney dysfunction.

Design outcomes

Primary

MeasureTime frame
the sensitivity of LVGLPS values for prediction of coronary atherosclerotic heart disease;

Secondary

MeasureTime frame
Positive predictive value;Change in conventional echocardiography parameters;Change in receiver operating characteristic (ROC) curve for prediction of high-risk coronary atherosclerotic heart disease using LVGLPS values;

Countries

China

Contacts

Public ContactWenjun Zhang

Taihe Hospital

wenjunth36@163.com+86 15071594315

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 27, 2026