Gastroesophageal reflux-induced chronic cough
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years old; 2. Cough duration>8weeks; 3. No wheezing,hemoptysis,fever,etc,No rales in the lungs,General treatment,including antibiotics,is ineffective; 4. The chest radiograph showed no abnormalities; 5. Pulmonary function test: FEV1/FVC=70%, FEV1>80% of the expected value; 6. To be able to understand and correctly complete the above scoring table.
Exclusion criteria
Exclusion criteria: Other common causes such as cough variant asthma,upper airway cough syndrome and eosinophilic bronchitis and other chronic cough,or ineffective treatment for these cause should be excluded or GERC, altuough the diagnosis of disease after treatment, but can not completely control cough suspected with GERC.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cough symptom score;Reflux Symptom Index;Capsaicin cough susceptibility test;Multichannel intraluminal esophageal impedance and pH monitoring; | — |
Countries
China
Contacts
Department of respiratory medicine, Shanghai Tongren Hospital