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Clinical study of the value of Reflux Symptom Index(RSI) alone or combined with GerdQ in the diagnosis of GERC

Effects of functional changes in esophagus on efficacy of treatment with baclofen in patients with gastroesophageal reflux-induced chronic cough

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DDD-17012587
Enrollment
Unknown
Registered
2017-09-05
Start date
2017-10-01
Completion date
Unknown
Last updated
2017-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal reflux-induced chronic cough

Interventions

Sponsors

Tongji Hospital, Tongji University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 80 years old; 2. Cough duration>8weeks; 3. No wheezing,hemoptysis,fever,etc,No rales in the lungs,General treatment,including antibiotics,is ineffective; 4. The chest radiograph showed no abnormalities; 5. Pulmonary function test: FEV1/FVC=70%, FEV1>80% of the expected value; 6. To be able to understand and correctly complete the above scoring table.

Exclusion criteria

Exclusion criteria: Other common causes such as cough variant asthma,upper airway cough syndrome and eosinophilic bronchitis and other chronic cough,or ineffective treatment for these cause should be excluded or GERC, altuough the diagnosis of disease after treatment, but can not completely control cough suspected with GERC.

Design outcomes

Primary

MeasureTime frame
Cough symptom score;Reflux Symptom Index;Capsaicin cough susceptibility test;Multichannel intraluminal esophageal impedance and pH monitoring;

Countries

China

Contacts

Public ContactLi Yu

Department of respiratory medicine, Shanghai Tongren Hospital

96778@tongji.edu.cn+86 13816699078

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026