Breast Cancer
Conditions
Interventions
Gold Standard:Breast cancer local recurrence or distant metastasis of the reference standard: physical examination, breast ultrasound, head?chest and abdomen enhanced CT, head MRI, bone ECT scan, tumo
blood 
MTDH
Sponsors
Affiliated Nanhua hospital, University of South China
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Aged 18-80 years old; estrogen receptor-positive breast cancer patients; Pathology I to III stagy; tolerant tamoxifen long-term treatment; agreed to participate in clinical trials; to complete the extraction of peripheral blood and successful detection of ctDNA MTDH.
Exclusion criteria
Exclusion criteria: Clinical advanced breast cancer; estrogen receptor-negative breast cancer patients; do not accept or can not tolerate tamoxifen long-term treatment; do not agree to participate in clinical trials; can not complete the peripheral blood extraction or can not detect ctDNA MTDH.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| physical examination;breast ultrasound;head?chest and abdomen enhanced CT;bone ECT scan;tumor standard test: CA125, CA153, CEA; | — |
Primary
| Measure | Time frame |
|---|---|
| peripheral blood ctDNA MTDH;tissue pathology; | — |
Countries
China
Contacts
Public ContactSong Wang
Affiliated Nanhua hospital, University of South China
Outcome results
None listed