Parkinson's Disease
Conditions
Interventions
Gold Standard:Diagnosis of Parkinson disease needs to meet 3 or more: unilateral onset
resting tremor
progressive course
long term asymmetry, the most obvious symptoms is the onset side
a good response to levodopa (70% ~ 100%)
levodopa induced chorea
a reaction of levodopa lasts 5 years or more
clinical course last
apparatus
As 
shown 
in 
Figure 
1, 
The 
ultrasound 
IE33-BOMJH1 
Sponsors
Department of Neurology, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital
Eligibility
Sex/Gender
All
Age
36 Years to 84 Years
Inclusion criteria
Inclusion criteria: 67 Parkinson's disease patients in our research came from Department of Neurology, Fujian Medical University Union Hospital. They were diagnosed by Queen Square Brain Bank UK PDS Brain Bank Criteria for the diagnosis of PD as the case group. Their ages were ranged from 36 to 84 years old, the average age was (67.18 ± 9.912) years old. All PD patients underwent UPDRS-III, and Hoehn-Yahr Rating Scale (H-Y). The UPDRS results can be divided into mild (below 10 points), moderate (11-20), severe (21-30).
Exclusion criteria
Exclusion criteria: In this research, 68 participants, without family history of PD and ruling out Parkinson’syndrome, Vascular Parkinsonism and the other extrapyramidal disease, were recruited as the control group. The both groups matched in age and gender.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the area of the echogenic signals in the substantia nigra;the intensity of the echogenic signals in the substantia nigra; | — |
Countries
China
Contacts
Public ContactQinyong Ye
Department of Neurology, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital
Outcome results
None listed