Age related macular degeneration
Conditions
Interventions
Gold Standard:
Index test:
Sponsors
Shanghai Tenth People's Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. =10 small drusen or 15 intermediate drusen or large drusen. 3a: without drusen pigment epithelium detachment; 3b: with drusen pigment epithelium detachment; 3. geographic atrophy involving the fovea, or at least 350um away from the fovea; 4. exudative age related macular degeneration, including without drusen pigment epithelium detachment; serous or hemorrhagic retina detachment; choroidal neovascularization membrane(CNVM) with sub retinal or sub pigment epithelium hemorrhage or fibrosis, or scars after AMD treatment. 5a: serous pigment epithelium detachment without CNVM, 5bCNVM or disiciform scar.
Exclusion criteria
Exclusion criteria: 1. Anterior segment inflammation, such as active conjunctivitis, keratitis and uveitis; 2. Fundus lesion except AMD such as macular hole, macular edema, high myopia, retinal vascular obstruction; 3. Diabetes, carcinoma, Alzheimer's disease and other systemic disease; 4. Could not complete examination and trial due to other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| miRNA-27a;miRNA-29b; | — |
Countries
China
Contacts
Public ContactJing Yu
Shanghai Tenth People's Hospital
Outcome results
None listed