Diffuse or focal lesions of non cardiac organs
Conditions
Interventions
Gold Standard:
Index test:
Sponsors
Shenzhen children's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Clinical diagnosis of non cardiac organ diffuse lesions or non contrast enhanced ultrasound examination showed non cardiac organs focal lesions; (2) in the past 1 months, dynamic CE-CT or CE-MRI tests have been carried out, or plans to carry out a dynamic CE-CT examination or histological biopsy within the month of the study, and may provide the original image (or copy) of the subjects; (3) subjects were 4 to 18 years old, to apply for non enhanced ultrasound or ultrasound guided renal biopsy of the hospital or outpatient; (4) the subjects have the ability and willingness to comply with the procedures, the subject and their legal guardians signed the informed consent.
Exclusion criteria
Exclusion criteria: (1) there is a fatal disease in the patient (i.e., no more than 6 months); (2) subjects had previously received renal SonoVue angiography; (3) subjects had received or were receiving systemic or local chemotherapy or radiotherapy; (4) the participants were involved in another clinical trial using an unregistered drug, or less than 30 days after the completion of such clinical trials; (5) subjects with eggs or egg products allergy (body rash, shortness of breath, mouth or throat swelling, hypotension or shock symptoms); (6) known to be allergic to any ingredient of six fluoride or SonoVue; (7) the subjects in the examination within 24 hours before receiving contrast agent (such as iodinated X-ray contrast agent, magnetic resonance imaging contrast agents or other ultrasound contrast agent) examination; (8) the researchers believe that the subjects are not fit to participate in the study; (9) the subjects had a right to left shunt, severe pulmonary hypertension (pulmonary artery pressure > 90 mmHg) or uncontrolled systemic hypertension; (10) patients with coronary artery disease (Kawasaki), echocardiography, abnormal, or exercise drug test were abnormal; (11) subjects had recently suffered a heart disease, or other clinical instability factors (such as the recent ECG, laboratory or clinical symptoms of acute heart failure), III/IV heart failure or severe arrhythmia; (12) subjects had a history of respiratory distress syndrome, severe pulmonary emphysema, pulmonary vasculitis, or embolism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specific diagnosis;benign or malignant diagnosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse drug reactions; | — |
Countries
China
Contacts
Public ContactXIA BEI
Shenzhen Children's Hospital
Outcome results
None listed