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Primary clinical diagnosis test of preimplantation diagnosis (PGD) for embryos with balanced chromosomal translocation

Primary clinical diagnosis test of preimplantation diagnosis (PGD) for embryos with balanced chromosomal translocation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-DDD-16007841
Enrollment
Unknown
Registered
2016-01-27
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chromosomal balanced translocation

Interventions

Gold Standard:
Index test:

Sponsors

Reproductive and genetic Hospital of Citic- Xiangya
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Age<=35y, BMI<=27kg/m2; 2. Patients with balanced translocation (Excluding Robertsonian translocation, the breakpoint is adjacent to centromere or telomere); 3. bilateral ovaries, FSH< 8mIU/ml; 4. signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Endometriosis disease; 2. uterine malformation, multiple uterine myoma, uterine intramural myoma >3cm, submucous myoma; 3. intrauterine adhesions history, history of uterine cavity effusion of unknown cause; 4. the previous history of abnormal thyroid function; 5. history of hypertension, systolic pressure >=150mmHg, DBP >=90mmHg; 6. previous or ongoing epilepsy, diabetes, cardiovascular disease, gastrointestinal diseases, liver disease, kidney disease, lung disease; 7. the woman of smoking, alcoholism, drug addiction; 8. cervical biopsy showed CIN I level and above.

Design outcomes

Primary

MeasureTime frame
Chromosomal balanced translocation ;—

Countries

China

Contacts

Public ContactHu Liang
lianghu7@gmail.com+86 731 88395668-6335

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026