Carcinomas, Hepatocellular
Conditions
Interventions
Gold Standard:
Index test:
Sponsors
Renji Hospital, Shanghai JiaoTong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Benign liver disease Group: 1. Patients with chronic hepatitis or hepatic cirrhosis; 2. No history of HCC at an early age; 3. Confirmed diagnosis of HBV, HCV or non-virus hepatitis(alcoholic liver disease or non-alcoholic liver disease), regardless of whether receiving treatment or severty of the diease; 4. Receive no treatment relating to blood products up to 3 months before blood sampling(such as blood transplantation or Interleukin treatment). Hepatocellular Carcinoma Group: 1. Confirmed HCC diagnosis, regardless of the cause (HBV, HCV, alcoholic or non-Alcoholic). Make a definitive diagnosis of HCC by biopsy up to seven days before blood sampling If possible; 2. No history of HCC at an early age; 3. Receive no treatment for HCC before blood sampling,including operation, transplantation, radiotherapy, chemotherapy, etc.
Exclusion criteria
Exclusion criteria: For all patients 1. Minor patients (under 18 years of age); 2. Pregnant women; 3. Patients with actions limited by judiciary; 4. HCC patients received biopsy in 7 days before blood sampling; 5. Receive treatment relating to blood products in 3 months before blood sampling (such as blood transplantation or Interleukin treatment).
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| AFP;overall survival;ALT;AST;HBV markers;HCV markers; | — |
Primary
| Measure | Time frame |
|---|---|
| circulating tumor cells;recurrence rate; | — |
Countries
China
Contacts
Public ContactXIA QIANG
Outcome results
None listed