brain death
Conditions
Interventions
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. aged =18 years old; 2. deep coma, absence of brainstem reflexes, and fulfill at least two of the three confirmatory tests (SLSEP, EEG and TCD); 3. fulfill the AP prerequisites: bladder or rectal temperature =36.5 degree C, systolic blood pressure maintained =90mmHg or mean arterial pressure =60mmH, preoxygenation with 100% oxygen for 10-15min to an arterial partial pressure of oxygen (PaO2) =200mmHg; 4. invasive arterial blood pressure monitoring and bedside arterial blood gas (ABG) analysis; 5. consent from the patient surrogates.;Inclusion criteria: 1. aged =18 years old; 2. deep coma, absence of brainstem reflexes, and fulfill at least two of the three confirmatory tests (SLSEP, EEG and TCD); 3. fulfill the AP prerequisites: bladder or rectal temperature =36.5 degree C, systolic blood pressure maintained =90mmHg or mean arterial pressure =60mmH, preoxygenation with 100% oxygen for 10-15min to an arterial partial pressure of oxygen (PaO2) =200mmHg; 4. invasive arterial blood pressure monitoring and bedside arterial blood gas (ABG) analysis; 5. consent from the patient surrogates.;Inclusion criteria: 1. aged =18 years old; 2. deep coma, absence of brainstem reflexes, and fulfill at least two of the three confirmatory tests (SLSEP, EEG and TCD); 3. fulfill the AP prerequisites: bladder or rectal temperature =36.5 degree C, systolic blood pressure maintained =90mmHg or mean arterial pressure =60mmH, preoxygenation with 100% oxygen for 10-15min to an arterial partial pressure of oxygen (PaO2) =200mmHg; 4. invasive arterial blood pressure monitoring and bedside arterial blood gas (ABG) analysis; 5. consent from the patient surrogates.;Inclusion criteria: 1. aged =18 years old; 2. deep coma, absence of brainstem reflexes, and fulfill at least two of the three confirmatory tests (SLSEP, EEG and TCD); 3. fulfill the AP prerequisites: bladder or rectal temperature =36.5 degree C, systolic blood pressure maintained =90mmHg or mean arterial pressure =60mmH, preoxygenation with 100% oxygen for 10-15min to an arterial partial pressure of oxygen (PaO2) =200mmHg; 4. invasive arterial blood pressure monitoring and bedside arterial blood gas (ABG) analysis; 5. consent from the patient surrogates.;Inclusion criteria: 1. aged =18 years old; 2. deep coma, absence of brainstem reflexes, and fulfill at least two of the three confirmatory tests (SLSEP, EEG and TCD); 3. fulfill the AP prerequisites: bladder or rectal temperature =36.5 degree C, systolic blood pressure maintained =90mmHg or mean arterial pressure =60mmH, preoxygenation with 100% oxygen for 10-15min to an arterial partial pressure of oxygen (PaO2) =200mmHg; 4. invasive arterial blood pressure monitoring and bedside arterial blood gas (ABG) analysis; 5. consent from the patient surrogates.
Exclusion criteria
Exclusion criteria: 1. arterial partial pressure of carbon dioxide unable to decrease to 45mmHg or below; 2. receive extracorporeal membrane oxygenation (ECMO) treatment; 3. physician or surrogates refuse the AP.;Exclusion criteria: 1. arterial partial pressure of carbon dioxide unable to decrease to 45mmHg or below; 2. receive extracorporeal membrane oxygenation (ECMO) treatment; 3. physician or surrogates refuse the AP.;Exclusion criteria: 1. arterial partial pressure of carbon dioxide unable to decrease to 45mmHg or below; 2. receive extracorporeal membrane oxygenation (ECMO) treatment; 3. physician or surrogates refuse the AP.;Exclusion criteria: 1. arterial partial pressure of carbon dioxide unable to decrease to 45mmHg or below; 2. receive extracorporeal membrane oxygenation (ECMO) treatment; 3. physician or surrogates refuse the AP.;Exclusion criteria: 1. arterial partial pressure of carbon dioxide unable to decrease to 45mmHg or below; 2. receive extracorporeal membrane oxygenation (ECMO) treatment; 3. physician or surrogates refuse the AP.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AP successful rate;Arterial blood gas analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of AP test; | — |
Countries
China
Contacts
Public ContactYingying Su;Yingying Su;Yingying Su;Yingying Su;Yingying Su ;;;;
Xuanwu Hospital Capital Medical University;Xuanwu Hospital Capital Medical University;Xuanwu Hospital Capital Medical University;Xuanwu Hospital Capital Medical University;Xuanwu Hospital Capital Medical University
Outcome results
None listed