hepatocellular carcinoma
Conditions
Interventions
HCC group :Gd-EOB-DTPA-enhanced MRI
healthy group :Gd-EOB-DTPA-enhanced MRI
Sponsors
Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. To be aged between 18-70; follow the standard of AASLD, first diagonosis of HCC, BCLC-A to BCLC-B; 2. no obvious distant metastasis, prediction of major liver resection(>3 segment); 3. Child A or B; 4. no allergic response to contrast, before operation, have the Gd Eob DTPA-enhanced MRI in 4 weeks,ICG and CT liver volume measurement in 1 weeks; 5. have the liver basic diseases; 6. no abnormal cardiopulmonary function; 7. avoid the harmful operation to the liver function during operative time; 8. the patients know the disease condition and the treatment project and the risk of surgery; 9. all volunteers,signing the informed consent form for clinical trial.
Exclusion criteria
Exclusion criteria: 1. have the difficult to follow up, such as :foreign,HK,macao,taiwan; 2. patients who refuse to sign the informed consent form; 3. uncertain clinical HCC diagnosis; 4. allergic to the contrast; 5. early recurrence and metastasis result in death postoperative; 6. BCLC-C or Child C; 7. have mild liver resection (<3 segment); 8. have the renal failure; 9. not primary hepatic tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hepatic extraction fraction;clearance of indocyanine green;CT liver volume measurement;pathological grade of liver cirrhosis; | — |
Secondary
| Measure | Time frame |
|---|---|
| tumor location;tumor size;tumor number;tumor pathological;HBV-DNA;blood loss intraoperative;time of operation;time of hepatic hilar occlusion; | — |
Countries
China
Contacts
Public ContactLi Xuesong
Outcome results
None listed