liver fibrosis
Conditions
Interventions
Gold Standard:
Index test:
Sponsors
The First Affiliated Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. patients between the 18 to 65 years of age, non-limited gender; 2. Within two weeks of the FibroTouch checkup, there are requested liver biopsy histological specimens; Using the liver biopsy needle of 16G or 14CT, Puncture and remove more than two centimeters long liver tissue (Including at least eleven portal areas, no fewer than six complete portal area and more than one centimeters minimum length of specimen); 3. Willing and able to abide and complete all study procedures; 4. Willing and can offer written informed consent form by the patient or patient’s the legal guardian.
Exclusion criteria
Exclusion criteria: 1. The people who may have the active or suspected cancer or history of malignant tumor by evidence, as well as the people who have the liver malignant tumors injury, cann’t participate in this study; 2. The people who have the history of a high alcohol intake, 40 gram/day for male and 40 gram/day for female((alcohol intake(g) = the amount of drinking(ml)*alcohol content%(v/v)*0.8(g/ml), 1g alcohol is the equal of 25-40ml beer, 8-10ml yellow rice wine, 5-12ml wine, 3-7ml health care wine or white spirit)), or abuse drug by evidence; 3. Alcoholic liver disease, hepatitis C; 4. Pregnant or lactating women, the people who have a pregnant plan and don't want to birth control in the study period; 5. the peoplewith history of organ transplantation or existing functional graft (except the cornea or hair graft); 6. The people with wound on the right upper abdomen recently; 7. The people who have the historyof serious illness, or other evidence shown that the patient have serious illness or don't fit to participate in the experiment; 8. The people who participate in other clinical research at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver stiffness;liver pathology; | — |
Contacts
Public ContactBIHUI ZHONG
Outcome results
None listed