Breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. invasive breast cancer is confirmed by preoperative hollow needle aspiration biopsy; 2. the tumor is unilateral, single; 3. preoperative chest radiograph, abdominal ultrasound and systematic bone scan confirmed no metastases in lung, liver or bone, if necessary, additional chest or abdominal CT or MRI should be taken; 4. tumor is located in the central, medial or lateral area; 5. tumor size >=5.0 cm; 6. ipsilateral ALN are swollen, confluenced with each other or adhered with other tissue; 7. clinical ultrasound, CT or MRI shows remarkable IMN metastasis; 8. neoadjuvant chemotherapy for 2-4 courses before surgery; 9. no malignant tumor located in other sites of body.
Exclusion criteria
Exclusion criteria: 1. with serious cardiac or pulmonary diseases, unable to tolerate the operation; 2. with pleura adhesion or lung adhesion or case history of thoracic operation; 3. inflammatory breast cancer; 4. breast cancer in pregnancy or lactation; 5. chemotherapy history in breast area.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Internal mammary sentinel lymph node detection rate; | — |
Countries
China