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Expressions of Eph/Ephrin and Rho GTPases in sarcomeres in patients with chronic myofascial pain syndrome

Expressions of Eph/Ephrin and Rho GTPases in sarcomeres in patients with chronic myofascial pain syndrome

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-CPR-15007329
Enrollment
Unknown
Registered
2015-10-02
Start date
2015-11-05
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myofascial pain syndrome

Interventions

Normal Group(Group N):biopsy of normal upper trapezius
Biopsy Group(Group B):Biopsy of TrPs plus injection of long-acting analgetics
Injection Group(Group I):Injection of long-acting analgetics

Sponsors

Qili Hospital of Shandong Universtiy
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. aged 20-65 years; 2. with a dignosed myofascial pain syndrome; 3. whose myofascial trigger points are located in upper trapezius; 4. with chronic pain lasted longer than 2 months; 5. whose skin of injection has no infection; 6. Subjects or their legal guardians have signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients' pain is resulted from neoplasm metastasis; 2. Patients suffered from sepsis; 3. Patients suffered from coagulation disorders.

Design outcomes

Primary

MeasureTime frame
VAS score (before therapy;3 days/1 week/2 weeks/1month/3months after therapy;yellow value(immunohistochemistry);absorbance at 490 nm(RhoA/Cdc42/Rac1 Elisa);absorbance at 490 nm(RhoA/Cdc42/Rac1 Glisa);

Secondary

MeasureTime frame
Frequency of pneumothorax;

Countries

China

Contacts

Public ContactFeng Qi
qifeng66321@sina.com+86 18560083756

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026