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Activated eosinophils in the muscle layer of esophagus involved in the pathogenesis of achalasia

Activated eosinophils in the muscle layer of esophagus involved in the pathogenesis of achalasia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-COC-17011979
Enrollment
Unknown
Registered
2017-07-13
Start date
2014-07-01
Completion date
Unknown
Last updated
2017-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Achalasia

Interventions

experimental group:esophageal muscle biopsies and mucosal tissues were taken during POEM
control group:esophageal muscle biopsies and mucosal tissues were taken during surgery

Sponsors

Tianjin Medical University General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Diagnosed with a comprehensive preoperative evaluation was completed for all patients, which included assessment by the Eckardt symptom scoring system, upper gastrointestinal endoscopy, HRM and timed-barium swallow

Exclusion criteria

Exclusion criteria: Patients with previous gastric and/or esophageal surgery, Barrett's esophageal lesions, esophageal stricture, liver cirrhosis and/or esophageal varices, active esophagitis, connective tissue diseases, allergic diseases, pregnancy, hemopathy, hiatal hernia, and other coagulopathy

Countries

China

Contacts

Public ContactZhao Wei

Tianjin Medical University General Hospital

zhaoweihotstone@yeah.net+86 15022327482

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026