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The effect of hyperhomocystinemia on the morbidity of contrast-induced nephropathy in patients with coronary heart disease.And a A combination of folic acid and B-group vitamins therapy on the incidence of contrast-induced nephropathy in high homocysteine patients with stable coronary artery disease.

The effect of hyperhomocystinemia on the morbidity of contrast-induced nephropathy in patients with coronary heart disease.And a A combination of folic acid and B-group vitamins therapy on the incidence of contrast-induced nephropathy in high homocysteine patients with stable coronary artery disease.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-COC-16009057
Enrollment
Unknown
Registered
2016-08-21
Start date
2016-08-25
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

contrast induced nephropathy

Interventions

Hcy15µmol/L Group:Nil
Hcy>15µmol/L Group:oral folic acid and Vitamin B

Sponsors

Department of Cardiology, First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients were eligible to participate if theywere aged =18 years and =75 Years;(2) All pa?tients admitted to the study with stable angina or unstable angina and diagnosed by Holter , standard 12-lead elec?trocardiogram (ECG),exercise stress test. (3) Patients had not taken folic acid or B-group vitamins nearly one year .

Exclusion criteria

Exclusion criteria: (1) STEMI or NSTEMI;(2) severe congestive heart failure ,NYHA II–IV; (3) acute renal failure;(4) those refuse take folic acid or B-group vitamins;(5)prior PCI or CABG.

Design outcomes

Primary

MeasureTime frame
serum creatinine;—

Countries

China

Contacts

Public ContactXu Hao

Cardiology Department, the First Affiliated Hospital of Zhengzhou University

691475813@qq.com+86 18768879691

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026