Chronic Obstructive Pulmonary Disease
Conditions
Interventions
viru-induced AECOPD group, non-virus induced AECOPD group, stable COPD group, healthy controls:sputum induction
Sponsors
College of Basic Medical Sciences, Jilin University
Eligibility
Sex/Gender
All
Age
16 Years to 100 Years
Inclusion criteria
Inclusion criteria: All of the patients were diagnosed with COPD according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2011 criteria (forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC)<70%, and post-bronchodilator FEV1<80%). AECOPD was defined with at least two major symptoms (increased dyspnea, enhanced cough or increased sputum production) or one major and one minor symptom (nasal discharge/congestion, wheeze, sore throat, cough) for at least 2 consecutive days.
Exclusion criteria
Exclusion criteria: Patients with a history of myocardial infarction, unstable angina, congestive heart failure, renal failure, cancer, pulmonary interstitial fibrosis, asthma, anti-virus treatment or currently active tuberculosis were excluded. In addition, COPD patients who were unconscious or declined to participate were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory mediators; | — |
Countries
China
Contacts
Public ContactFang Wang
College of Basic Medical Sciences, Jilin University
Outcome results
None listed