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Role and Regulation of Inflammation in Tracheal Stenosis after Endotracheal Intubation

Role and Regulation of Inflammation in Tracheal Stenosis after Endotracheal Intubation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-COC-16008132
Enrollment
Unknown
Registered
2016-03-22
Start date
2016-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tracheal stenosis after intubation

Interventions

Tracheal stenosis after intubation:Test by ELISA
No tracheal stenosis after intubation:Test by ELISA
Normal:Test by ELISA
All groups:western blot

Sponsors

Department of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
13 Years to 86 Years

Inclusion criteria

Inclusion criteria: 1. Tracheal intubation stenosis (10-50 cases); 2. tracheal intubation without stenosis group (10-50 cases, tracheal intubation time is more than or equal to 3 days); 3. normal group (10-50 patients from non smoking lung cancer surgery resection specimens of surrounding normal lung tissue).

Exclusion criteria

Exclusion criteria: 1. Congenital tracheal stenosis, tracheal neoplasms, connective tissue diseases caused by tracheal stenosis, tracheal and bronchial tuberculosis, caused by foreign bodies in trachea stenosis; 2. within 7 days using macrolide drugs, hormone and immune suppression or enhancement treatment shall be stopping for a week.

Design outcomes

Primary

MeasureTime frame
TGF-ß;VEGF;IL-8;IL-6;TNF-a;gene sequencing;HDAC2;—

Countries

China

Contacts

Public ContactGuang-nan Liu

Department of Respiratory Medicine, First Affiliated Hospital of Guangxi Medical University

gnliu63@hotmail.com+86 15994316399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026