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The changes of AMPK - PGC1alpha- SIRT3 axis and MnSOD, the main indicator of oxidative stress, in skeletal muscle of diabetic patients

The changes of AMPK -PGC1alpha- SIRT3 axis and MnSOD, the main indicator of oxidative stress, in skeletal muscle of diabetic patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-COC-15007025
Enrollment
Unknown
Registered
2015-09-02
Start date
2015-09-09
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

None listed

Sponsors

Metabolic Disease Hospital of Tianjin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Type 2 diabetic and nondiabetic patients

Exclusion criteria

Exclusion criteria: 1. cardiovascular disease; 2. neoplastic disease; 3. neurodegenerative disease; 4. acute inflammation.

Design outcomes

Primary

MeasureTime frame
AMPK;PGC1 alpha;SIRT3;MnSOD;FOXO3a;—

Secondary

MeasureTime frame
fasting plasma glucose;blood lipid;markers of hepatic function;markers of renal function;glycosylated hemoglobin;—

Countries

China

Contacts

Public ContactYue Guan
guanyue@medmail.com.cn+86 13612199277

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026