psoriasis
Conditions
Interventions
Psoriasis group :treated with blood heat clearing decoction
normal group :nothing
Sponsors
Beijing Hospital of TCM affliated to CMU
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The included individuals must comply with all the following criteria. 1. Psoriasis group 1) Meeting the clinical diagnosis criteria of psoriasis; 2) Meeting the clinical diagnosis criteria of psoriasis blood-heat syndromes of T.C.M.; 3) Male or female patients aged 18-65 years old; 4) Written informed consent for participating. 2. Control group 1) Healthy, nonpsoriatic volunteers; 2) Male or female patients aged 18-65 years old; 3) Written informed consent for participating.
Exclusion criteria
Exclusion criteria: 1) Obscure in syndrome differentiation, not belonging to blood-heat syndromes; 2) Pregnant and lactating women; 3) Taking corticosteroids, phototherapy, systemic therapies and other T.C.M. treatment within 4 weeks; Use of corticosteroids, vitamin D analogues, keratolytics or coal tar within 2 weeks; 4) Renal or liver impairment, active infection, immunosuppression or other serious concomitant illness; 5) Accompany with skin tumor; 6) Patients with erythrodermic, pustular, and only palmoplantar forms of psoriasis, and patients with psoriatic arthritis were excluded; 7) Allergic to components of the decoction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lymphocyte subpopulation;cytokine;gene expression;DNA methylation;Psoriasis area and severity index;syndrome differentiation; | — |
Countries
China
Contacts
Public ContactYajun Li
Outcome results
None listed