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Pathway regulates OPG / RANKL / RANK signaling system to explore kidney type of osteoporotic vertebral fractures reconstruction molecular mechanisms based on Notch signaling

Pathway regulates OPG / RANKL / RANK signaling system to explore kidney type of osteoporotic vertebral fractures reconstruction molecular mechanisms based on Notch signaling

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-COC-15006296
Enrollment
Unknown
Registered
2015-04-22
Start date
2013-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoporotic vertebral compression fracture

Interventions

female OVCF:None
male OVCF:None
female non-osteoporosis group :None
male non-osteoporosis group :None

Sponsors

The First Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. meet the diagnostic criteria for primary osteoporosis and the Chinese people recommend diagnostic criteria for osteoporosis; 2. aged 55 to 80 years old; 3. signed informed consent.

Exclusion criteria

Exclusion criteria: 1. does not meet the primary osteoporosis diagnostic criteria; 2. younger than 55 years of age or over 80 years of age; 3. long-term use other drugs, can not be disabled by immediately; 4. late deformity, disability, loss of labor; 5. multiple drug allergies and allergies; 6. with liver, kidney, hematopoietic system, endocrine system diseases in primary and serious mental illness; 7. who is ready to participate in other clinical trials or persons.

Design outcomes

Primary

MeasureTime frame
Notch1;Jagged1;HES1;HES5;HEY1;—

Countries

China

Contacts

Public ContactZhang Shuncong
drzsc@sina.com+86 13602765101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026