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Study of the neuropsychology and neuroimaging in First-episode Schizophrenic Patients before and after treatment

Study of the neuropsychology and neuroimaging in First-episode Schizophrenic Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-COC-14005302
Enrollment
Unknown
Registered
2014-01-05
Start date
2011-11-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenic

Interventions

Sponsors

First Affiliated Hospital, College of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Study group: 1. patients provided their written and informed consent; 2. patients were between 13-45 years old, males and females; 3. patients with a DSM-IV clinical criteria for Schizophrenic episode; 4. right-handed; 5. patients who are experiencing their first depressive episode and did not use the antipsychotic drug. Control Group: 1. patients provided their written and informed consent; 2. patients were between 13-45 years old, males and females; 3. right-handed; 4. did not use the antipsychotic drug; 5. healthy.

Exclusion criteria

Exclusion criteria: Patients were excluded if they fell into any of the following categories: 1. had epileptic, Body metal patients and cerebral apoplexy; 2. had severe nerve, heart, liver, kidney, endocrine, blood system diseases or other disturb the estimate of study; 3. had organic mental disorders and mental retardation; 4. had drugs, alcohol or other psychotropic active substance abusers; 5. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
cognitive function;functional connectivity within default state netwo;the brain gray matter density;fractional anisotropy (FA) valus;regional homogeneity (ReHo) valus;PANSS score;

Countries

China

Contacts

Public ContactHuang Manli
hml1208@sina.com+86 13957162975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 1, 2026