Schizophrenic
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Study group: 1. patients provided their written and informed consent; 2. patients were between 13-45 years old, males and females; 3. patients with a DSM-IV clinical criteria for Schizophrenic episode; 4. right-handed; 5. patients who are experiencing their first depressive episode and did not use the antipsychotic drug. Control Group: 1. patients provided their written and informed consent; 2. patients were between 13-45 years old, males and females; 3. right-handed; 4. did not use the antipsychotic drug; 5. healthy.
Exclusion criteria
Exclusion criteria: Patients were excluded if they fell into any of the following categories: 1. had epileptic, Body metal patients and cerebral apoplexy; 2. had severe nerve, heart, liver, kidney, endocrine, blood system diseases or other disturb the estimate of study; 3. had organic mental disorders and mental retardation; 4. had drugs, alcohol or other psychotropic active substance abusers; 5. Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function;functional connectivity within default state netwo;the brain gray matter density;fractional anisotropy (FA) valus;regional homogeneity (ReHo) valus;PANSS score; | — |
Countries
China