Gestational diabetes mellitus
Conditions
Interventions
Gestational diabetes mellitus (GDM):Diet and exercise control, insulin treatment for serious illness
normal glucose tolerance (NGT).:not intervention
Sponsors
Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Gestational diabetes mellitus (GDM) is defined as a carbohydrate intolerance of varying degrees of severity with onset or first recognition during pregnancy. All pregnant women were from Second Affiliated Hospital of Chongqing Medical University routinely screened for GDM at 26-32 weeks of gestation. GDM is diagnosed according to the criteria of the Chinese Diabetes in Pregnancy Society after a 75g oral glucose load (OGTT)and is defined as fasting plasma glucose levels higher than 5.6 mmol/L or plasma glucose levels higher than 10.3 mmol/L, 8.6 mmol/L, and 6.7 mmol/L 1-h, 2-h, and 3-h after OGTT, respectively.
Exclusion criteria
Exclusion criteria: previously-diagnosed diabetes, maternal hypertension, asthma, polycystic ovaries,preeclampsia, liver diseases, kidney diseases and use of glucocorticoids during pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| maternal cortisol,Fasting plasma glucose,Fasting insulin;Umbilical cord cortisol;11-beta HSD gene,protein expression in placental tissue;alters insulin signaling in skeletal muscle;alters insulin signaling in adipose tissue; | — |
Countries
China
Contacts
Public ContactXiaoqiu Xiao
Outcome results
None listed