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NLRP3 expression in gingival tissue of periodontitis patient and its significance

NLRP3 expression in gingival tissue of periodontitis patient and its significance

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-CCS-13004068
Enrollment
Unknown
Registered
2013-09-21
Start date
2013-12-21
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

2:none

Sponsors

Guangdong Provincial Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria of physical healthy control group(PH) include no clinical signs of periodontitis(no periodontal pockets greater than or equal to 4mm, no bleeding on probing, no attachment loss and furcation involvement, no alveolar bone absorption), no history of periodontal disease and systemic disease treatment.The inclusion criteria of chronic periodontitis group(CP) were patients with PD>4mm, AL>1mm combined with alveolar bone absorption, the distance from CEJ to the alveolar crest>3mm(according to the American Society of Periodontology 1999 classification criteria for the diagnosis of periodontal disease).

Exclusion criteria

Exclusion criteria: The exclusion criteria comprise patients with systemic diseases and subjects who had taken systemic antibiotic, anti-in?ammatory, hormonal, osteoporosis and medications known to in?uence periodontal tissues in the 3 months prior to the start of the study; Pregnant or lactating women are also exclusive.

Design outcomes

Primary

MeasureTime frame
mRNA;protein;

Countries

China

Contacts

Public ContactXuan Dongying
xuanxuan187@126.com+86 13889903244

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026