Chronic Hepatitis B
Conditions
Interventions
acute hepatitis B:no
patients with chronic hepatitis B:no
Sponsors
The First Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Chronic hepatitis B: included a diagnosis of with persistent HBV infection more than one year. The patients should include the diagnosis of HBV DNA more than 104copies/mL, HBsAg and anti-HBc positive, anti-HBs negative and no history of antiviral treatment.Acute hepatitis B: patients with acute HBV infection completely recovered from the illness, exhibiting normalized serum transaminase levels and clearance of HBsAg and HBeAg from the serum within 6 months of the disease.
Exclusion criteria
Exclusion criteria: Patients were excluded if they had other mixed causes of chronic liver disease such as hepatitis C, alcohol abuse or autoimmune liver disease, or if they had a diagnosis of liver cirrhosis and hypersplenia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| transcription factor T-bet; | — |
Contacts
Public ContactLi Yongguo
Outcome results
None listed