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The function of C - type lectin Receptor, Dendritic cell - specific ICAM - 3 - grabbing Non - integrin (DC - SIGN) and molecular mechanism in immune abnormaies of atopic dermatitis.

The function of C - type lectin Receptor, Dendritic cell - specific ICAM - 3 - grabbing Non - integrin (DC - SIGN) and molecular mechanism in immune abnormaies of atopic dermatitis.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-CCC-14004609
Enrollment
Unknown
Registered
2014-03-23
Start date
2014-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis

Interventions

6:TLR block
6:DC-SIGN block therapy
6:TLR block and DC-SIGN block
6:Dust mites stimulus
6:None

Sponsors

Institute of Dermatology, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 45 Years

Inclusion criteria

Inclusion criteria: The diagnosis of AD according to Williams' criteria, disease severity was assessed quantitatively with SCORAD from mild to-severe AD.Volunteered for this study and signed informed consent.

Exclusion criteria

Exclusion criteria: ?Pregnant or lactating females; ?Any other situations not suitable for this study determined by the investigators.

Design outcomes

Primary

MeasureTime frame
the marker CD80/CD83/CD86 expression on dendritic;the cytokine of Dendritic cell culture supernatan;—

Countries

China

Contacts

Public ContactYao Xu

Institute of dermatology, Chinese Academyof Medical Sciences

dryao_xu@126.com+86 13512513536

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026