Primary immune thrombocytopenia
Conditions
Interventions
ITP patients:NA
Sponsors
First Affiliated Hospital of Xinjiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: The case inclusion criteria are as follows: 1. Conform to the diagnostic criteria of ITP: (1) decreased platelet counts in many laboratory tests; (2) Without splenmegaly; (3) Elevated or normal number of megakaryocytes in the bone morrow examination with dysmaturity; (4) With exception of other secondary thrombocytopenic purpura; 2. Without received platelet transfusions and splenectomy treatment; 3. Without used of corticosteroids, immunosuppressants or disabled a month or more; 4. Aged 18 to 75 years old, male or female; 5. volunteer to participate in clinical trial, and signed informed consent. The healthy contorl inclusion criteria are as follows: Healthy volunteers; Without fever and history of drug taking recently, Without ditinct dysfunction of heart, lung, liver, kidney and so on; The Families and volunteers Informed and signed informed consent.
Exclusion criteria
Exclusion criteria: With exception of other secondary thrombocytopenic purpura (eg: Aplastic anemia, Acute Leukemia, Myelodysplastic syndrome, Acute hematopoietic function stagnation and so on); Platelet transfusion history and taking immunosuppressant nearly a month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cytokines;PD-1;PD-L1; | — |
Countries
China
Contacts
Public ContactXinhong GUO
First Affiliated Hospital of Xinjiang Medical University
Outcome results
None listed