Skip to content

The role and mechanism investigate of Th17/Treg in the inflammatory response of adenomyosis

The role and mechanism reaserch of Th17/Treg in the inflammatory response of adenomyosis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-CCC-13003500
Enrollment
Unknown
Registered
2013-07-18
Start date
2012-10-08
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adenomyosis

Interventions

1:Flow cytometry analysis
2:mRNA expression level assay
3:ELISA assay
4:Immunohistochemistry staining

Sponsors

Jiangsu Provincial Hospital of Integrated Traditional and Western Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 50 Years

Inclusion criteria

Inclusion criteria: For study group (1) Aged 30 to 50, female; (2) patients with adenomyosis (diffuse or focal)was diagnosed according to the internatianal diagnostic criteria con?rmed who were subject to hysterectomy; (3) All people in both groups voluntarily joined this study with informed consents. For control group: (1) Aged 30 to 50, female; (2) Patients with leiomyomas, cervical intraepithelial neoplasia III, or cervical carcinoma in situ was diagnosed according to the internatianal diagnostic criteria confirmed who were subject to hysterectomy; (3) All people in both groups voluntarily joined this study with informed consents.

Exclusion criteria

Exclusion criteria: (1) Accompany with endometriosis, endometrial polyps, pelvic inflammatory disease and other in flammatory and autoimmune diseases; (2) With serious cadiovascular, liver, kideny,hyperlipidemia, hypertension, or mental diseases through history; (3) The suspected cases.

Design outcomes

Primary

MeasureTime frame
Regulatory T cell;T help cell 17;FOXP3;ROR?t;STAT3;IL-17A;TGF-ß1;CA125;

Secondary

MeasureTime frame
IL-6;IL-10;

Countries

China

Contacts

Public ContactGui Tao
guitaoemail@163.com+86 158 5078 4305

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 22, 2026