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Screening and identification of hURAT1 human urate transporter-related micro-RNA

Screen and identification of hURAT1 human urate transporter-related micro-RNA

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-CCC-13003397
Enrollment
Unknown
Registered
2013-07-08
Start date
2013-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary calculi

Interventions

A:urate calculus
B:non-urate calculus
C:no calculus

Sponsors

Urologic Institute, Southwest Hospital, Third Military Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Experiment are divided into uric acid stones group (A), non-uric acid stones group (B), control group (C), A, C recruited 30 patients each group, B group recruited 20 patients.AB group were enrolled standards: 1. aged 18-65 years old; 2. comply with percutaneous nephrolithotomy lithotripsy indications for surgery; 3. ECT tips ipsilateral normal or mildly impaired renal function. Group C patients were enrolled standards: 1. aged 18-65 years old; 2. normal renal function, not associated with urinary calculi in patients; 3. cancer patients met radical nephrectomy indications for surgery; 4. emergency trauma patients suffering from kidney resection surgical indications.

Exclusion criteria

Exclusion criteria: 1. aged 65 years; 2. neurological disease or cognitive dysfunction; 3. can not be corrected or uncorrected coagulopathy; 4. associated with diabetes, hypertension and other metabolic diseases; 5. accompanied by tuberculosis, hepatitis, HIV and other infectious diseases; 6. poor tolerance to anesthesia and surgery, such as: severe cardiopulmonary disease, coagulation.

Design outcomes

Primary

MeasureTime frame
micro-RNA;hURAT1 transporter protein;Blood biochemistry;Urine test;24h urine quantitative analysis;Stone analysis;

Countries

China

Contacts

Public ContactWeibing Li
liweibing1963@126.com+86 13320339989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026