Association study of GDF5 core promoter polymorphism with adolescent idiopathic scoliosis

Status

Active, not recruiting

Phases

Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR-CCC-09000531

Enrollment

Unknown

Registered

2009-09-07

Start date

2007-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adolescent idiopathic scoliosis

Interventions

Controls:Extract Genomic DNA, using Taqman assay genotype

Cases:Extract Genomic DNA, using Taqman assay genotype

Eligibility

Sex/Gender

All

Age

No minimum to 40 Years

Inclusion criteria

Inclusion criteria: The patients were diagnosed by clinical and standard standing posteroanterior radiographs examinations, and confirmed by magnetic resonance imaging to exclude the possibility of central system disorders of cerebrum and spinal cord. All participants should signed informed consent

Exclusion criteria

Exclusion criteria: Patients with other spinal diseases and without clinical examination/X-ray were excluded. Who do not signed informed consent were excluded.

Design outcomes

Primary

Measure	Time frame
genotype distribution, allele frequency;	—

Secondary

Measure	Time frame
the cases were stratified by sex, height and Cobb angle;	—

Countries

China

Contacts

Public ContactQing Jiang

qingj@nju.edu.com+86 025 83107033

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026