Asthma
Conditions
Interventions
control:no interventions, induce sputum using 3-5% hypertonic saline
asthma:no interventions, induce sputum using 3-5% hypertonic saline
Sponsors
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
12 Years to 60 Years
Inclusion criteria
Inclusion criteria: Asthma patients: including chronic stable and attack, without systemic steroid therapy within three months,no smoking, without autoimmune diseases, without chronic or acute infection. Control: healthy population.
Exclusion criteria
Exclusion criteria: Systemic steroid therapy within three months,smoking, autoimmune diseases, chronic or acute infection, airflow limitation except for asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The expression of Th17 cell in inducing sputum;The ratio of CD4+ T cell in peripheral blood;Concentration of cytokine in serum and inducing sputum; | — |
Secondary
| Measure | Time frame |
|---|---|
| The level of total serum IgE; | — |
Countries
China
Contacts
Public ContactShi Guochao
Outcome results
None listed