FindTrial
Sign In

The role of CD146 mediated Wnt5a/JNK signaling in podocyte injury and EMT like change in diabetic nephropathy

The role of CD146 mediated Wnt5a/JNK signaling in podocyte injury and EMT like change in diabetic nephropathy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-BRC-17012769
Enrollment
Unknown
Registered
2017-09-22
Start date
2017-05-08
Completion date
Unknown
Last updated
2017-10-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Nephropathy

Interventions

Microalbuminuria Group:null
Macroalbuminuria Group:null
Normal Control Group:null

Sponsors

Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients were selected according to the WHO diagnostic criteria for type 2 diabetes and the Mogensen staging criteria for diabetic nephropathy in patients with type 2 diabetes mellitus with diabetic nephropathy

Exclusion criteria

Exclusion criteria: Any type 1 diabetes, with autoimmune diseases, acute and chronic inflammatory or infectious diseases, trauma, cancer, dialysis or renal transplant recipients

Design outcomes

Primary

MeasureTime frame
Age;Gender;Weight;Blood Pressure;Body Mass Index;Duration of Diabetes;Diabetic Retinopathy;Peripheral Vascular Disease;Urine sCD146;Urine nephrin;—

Countries

China

Contacts

Public ContactNiansong Wang

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

wangniansong2008@163.com+86 18930177399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026