Skip to content

Screening the key candidate genes in the occurrence and development of early HCC using high-throughput sequencing

Screening the key candidate genes in the occurrence and development of early HCC using high-throughput sequencing

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-BON-17011202
Enrollment
Unknown
Registered
2017-04-20
Start date
2017-04-12
Completion date
Unknown
Last updated
2017-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver cancer

Interventions

Compensation group:Extraction of liver tissue
Decompensation group:Extraction of liver tissue
Early HBV group:Extraction of hepatocellular carcinoma
Early HBV group:Extraction of hepatocellular carcinoma tissue

Sponsors

People's Hospital of Deyang City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: HBV infection decompensated liver cirrhosis of the liver tissue (compensatory group) into the standard: a clear diagnosis of liver cirrhosis compensation period; HBV infection decompensated liver cirrhosis of the liver tissue (decompensated group) included in the standard: a clear diagnosis of decompensated liver cirrhosis. Compensatory and decompensation groups are required to meet the following inclusion criteria: (1) hepatitis B virus positive; (2) Age over 18 years old, under 60 years old. Early inclusion criteria for early hepatocellular carcinoma: (1) patients have not received chemotherapy, radiotherapy and targeted therapy; (2) no other cancer history; (3) a clear diagnosis of early hepatocellular carcinoma (TNMI);

Exclusion criteria

Exclusion criteria: Compensation group and decompensation group exclusion criteria: (1) HBV combined with HIV, TB (Mycobacterium tuberculosis) and other infected patients; (2) other hepatitis virus infected patients; (3) alcohol or drugs and other causes of cirrhosis; (4) have a history of cancer; (5) combined with other cancers including hepatocellular carcinoma; (6) combined with diabetes and other metabolic syndrome. Criteria for early hepatocellular carcinoma: (1) patients with cancer history; (2) patients with hepatocellular carcinoma with lymph node or other organ metastases.

Design outcomes

Primary

MeasureTime frame
lncRNA expression profile;mRNA expression profile;miRNA expression profile;

Countries

China

Contacts

Public ContactChengliang Yuan

People's Hospital of Deyang City

dyyuancl@163.com+86 0838-2418493

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026