Osteoporosis
Conditions
Interventions
Osteoporosis group:Collect patient samples
Control group:Collect healthy participant samples
Sponsors
People's Hospital of Deyang City
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: According to WHO standards, femoral neck or lumbar vertebrae bone density T =-2.5, the diagnosis of osteoporosis, T =-1 normal bone mass. Individuals included in the study had no history of drugs that might affect bone metabolism: glucocorticoids, estrogens, thyroid hormones, parathyroid hormone, fluoride, calcitonin, thiazide, barbiturate, Antiepileptic drugs, vitamin D and calcium preparations.
Exclusion criteria
Exclusion criteria: Previously suffering from bone metabolism diseases such as kidney disease, liver disease, thyroid disease, diabetes, hyperprolactinemia, ovariectomy, rheumatoid arthritis, ankylosing spondylitis, chronic abdominal bones and other adverse symptoms, Blood disease, and individuals who have undergone pathological fractures or traumatic fractures in the last year. Patients with hypertension, coronary atherosclerosis, myocardial infarction, cerebral infarction, and infectious disease were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Methylation chip detection;mRNA sequencing; | — |
Countries
China
Contacts
Public ContactYuehong Liu
People's Hospital of Deyang City
Outcome results
None listed