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Pain sensitivity in schizophrenia: neural mechanisms

Pain sensitivity in schizophrenia: neural mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-BOC-17013972
Enrollment
Unknown
Registered
2017-12-15
Start date
2018-04-05
Completion date
Unknown
Last updated
2017-12-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

schizophrenia

Interventions

patients:multisensory stimuli
healthy controls:multisensory stimuli

Sponsors

Beijing HuiLongGuan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: For patients: 1) DSM-V diagnosis of schizophrenia; 2) Drug dosage kept constant for > 1 month; 3) A total score of Positive and Negative Syndrome Scale (PANSS) ranged from 60 to 70; 4) Considered clinically stable with good cognitive function and speech intelligiblity by their treating physician; 5)Aged 18~50 years. For healthy controls' age and gender same as patients group.

Exclusion criteria

Exclusion criteria: For patients: 1) concomitant severe medical or neurological illness, comorbidity of any other DSM-V Axis I disorder, past or current substance abuse, high suicidal risk; 2) accepting the modified electric compulsive therapy in the past 6 months; 3) contraindications of MRI scanning (e.g., implanted metal objects, claustrophobia). For healthy controls: with a history of psychiatric illness or positive family history for schizophrenia or current concomitant physical pain.

Design outcomes

Primary

MeasureTime frame
perceived intensity of multisensory stimuli;brain response;

Countries

China

Contacts

Public ContactLi Hu

Institute of Psychology, Chinese Academy of Sciences

huli@psych.ac.cn+86 18310227286

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026