Schizophrenia
Conditions
Interventions
Sponsors
Beijing Anding Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Inclusive criteria of patients: 1. Sign the informed consent by the patient or their legal guardian; 2. Aged between 18 and 30. Men or female; 3. Diagnosed as schizophrenia according to the ICD-10 criteria; or in compliance with the risk syndrome of temporary intermittent psychiatric syndrome (SOPS), mild positive symptom syndrome and genetic risk and functional degradation of mental illness in psychiatric risk syndrome; 4. The course of disease is no more than 10 years; 5. Understand and cooperate with the research. Inclusive criteria of healthy person: 1. Sign the informed consent; 2. Aged between 18 and 30 years, male or female; 3. Have no diagnosis of any mental disorder in the ICD-10.
Exclusion criteria
Exclusion criteria: 1. Other mental disorders (including comorbidity) not listed in the inclusive criteria; 2. According to the researcher's judgment, subjects have the risk of suicide or injury to others; 3. According to the researcher's judgment, the MRI examination cannot be tolerated; 4. In the first 6 months before the research the subjects have used the electric convulsive treatment; 5. Substances or alcohol dependence according to DSM-IV criteria (except for fully relieved patients and caffeine, tobacco-dependent patients) when random grouping; 6. In the 4 weeks before randomization, opioid, amphetamine, barbiturates, cocaine, cannabis or hallucinogenic substances were abused according to DSM-IV standards; 7. According to the researcher's judgment, the physical condition of the subjects was unstable or inadequate (e.g. diabetes, angina, and hypertension); 8. subjects planning or operating this study; 9. Accordance to the local laws and regulations, subjects participate in other drug clinical trials in 4 weeks before admission; 10. Catatonic schizophrenia; 11. Do not cooperate with the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| psychology evaluation;fMRI scanning;Symptom assessment; | — |
Countries
China
Contacts
Public ContactJia Hongxiao
Beijing Anding Hospital, Capital Medical University
Outcome results
None listed