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The role of T helpers in immune mechanism of malignant ascites formation

The role of T helpers in immune mechanism of malignant ascites formation

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-BOC-17011724
Enrollment
Unknown
Registered
2017-06-21
Start date
2016-06-01
Completion date
Unknown
Last updated
2017-07-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant ascites

Interventions

healthy control :Vein puncture
malignant ascites:Vein puncture
ascites of portal hypertension:Vein puncture
malignant ascites:abdominocentesis
ascites of portal hypertension:abdominocentesis
healthy control:abdominocentesis

Sponsors

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: malignant ascites patients: 1. diagnosed as malignant ascites; 2. accepting abdominocentesis successfully. patients of portal hypertension: 1. SAAG(serum-ascites albumin gradaient)>1.1g/L; 2. diagnosed as liver cirrhosis, cardiac, Budd–Chiari syndrome, Sinusoidal obstruction syndrome or hepatic failure; 3. renal ascites.

Exclusion criteria

Exclusion criteria: patients of malignant or portal hypertension ascites: 1. accepting invasive therapy for ascites-related diseases; 2. in hospital for abdomin trauma in the past three months; 3. accppting chemotherapy, radiation, immunotherapy or anti-inflammatories near before or during specimen collection; 4. pregnant woman or psychotic inpatients.

Design outcomes

Primary

MeasureTime frame
treg cell;th1 cell;th2 cell;th17 cell;ifn-?;il-4;il-17;

Countries

China

Contacts

Public ContactSong Yuhu

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology

yuhusong@163.com+86 15007187581

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026