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Chronic periodontitis induce pyroptosis in gingival fibroblast cells

Chronic periodontitis induce pyroptosis in gingival fibroblast cells

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-BOC-17011626
Enrollment
Unknown
Registered
2017-06-11
Start date
2017-07-01
Completion date
Unknown
Last updated
2017-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis

Interventions

periodontitis group:none
normal group:none

Sponsors

West China Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Periodontitis group: 1. aged 18-80 years; 2. diagnosed as chronic periodontitis; 3. have indications of periodontal plastic surgery after scaling; 4. normal with vital signs and routine physical examination. Normal group: 1. aged 18-80 years; 2. have normal gingiva; 3. have indications of gingivoplasty; 4. normal with vital signs and routine physical examination.

Exclusion criteria

Exclusion criteria: (1) pregnancy, intention of pregnancy, lactation; (2) presence of severe systemic diseases; (3) use of antibiotics within 1 month; (4) diagnosed as aggressive periodontitis.

Design outcomes

Primary

MeasureTime frame
IL-1ß;caspase 1;—

Countries

China

Contacts

Public ContactHongmei Zhou

West China Hospital of Stomatology, Sichuan University

acomnet@126.com+86 028-85503480

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026