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Pathophysiological study of bone marrow mesenchymal stem cells in patients with acute myeloid leukemia

Pathophysiological study of bone marrow mesenchymal stem cells in patients with acute myeloid leukemia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-BOC-17010799
Enrollment
Unknown
Registered
2017-03-06
Start date
2017-03-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myeloid leukemia

Interventions

Treatment group Control group:in vitro culture
Treatment group Control group:cytarabine
Treatment group Control group:Adriamycin
Treatment group Control group:Daunorubicin

Sponsors

Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Diagnosed of having an Acute Myeloid Leukemia; 2. No limit in gender and the patients aged 3 to 80 years; 3. Signed a patient authorization form to use and disclose personal health information (or informed consent; participants under 18 years or thoese loss language ability can be signed by their guardians).

Exclusion criteria

Exclusion criteria: 1. Diagnosed of having an Chronic Myeloid Leukemia; 2. Participates in a concurrent interventional clinical trial (phase 1, 2 or 3 or a Compassionate Use or Early Access Program).

Design outcomes

Primary

MeasureTime frame
Survival and proliferation in vitro;IL8 expression level;Efflux rate of chemotherapeutic agents;apoptosis rate;Expression levels of cell cycle and apoptosis related proteins;Adipogenic and osteogenic differentiation;Expression profile of IL8 related genes;

Countries

China

Contacts

Public ContactTianxiang Pang

Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College

pang@ihcams.ac.cn+86 18630963859

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026