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Effect of Kashmanda Avaleha and Mashadi Modaka on weight gain and immune health in underweight adults

Efficacy of Kushmanda Avaleha and Mashadi Modaka on Anthropometric and Immune Parameters in adults with Karshya underweight A Randomized open label controlled Clinical Trial - Nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/114201
Enrollment
100
Registered
2026-07-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E46- Unspecified protein-calorie malnutrition

Interventions

None listed

Sponsors

Institute of Teaching and Research in Ayurveda, Jamnagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. BMI less than 18.5 kg/m2 2. Participants between 20 to 40 years of age. 3. Participants who are willing to participate in the study.

Exclusion criteria

Exclusion criteria: Participants having diagnosed systemic disorders such as cardiac diseases, diabetes mellitus, chronic renal failure, tuberculosis, acquired immunodeficiency syndrome, anorexia nervosa, or other significant systemic illnesses. Participants having Karshya underweight due to drug induced Addison disease, hyperthyroidism, anaemia induced undernourishment, or other endocrine and hormonal disorders. Participants with diagnosed psychiatric or psychological disorders, or those currently receiving pharmacological treatment for a mental health condition. Participants with a history of unintentional weight loss of five to ten percent or more within the past six months, or ten to twenty percent beyond six months. Participants with symptoms suggestive of malabsorption syndrome, including chronic diarrhoea, steatorrhea, unexplained weight loss, abdominal bloating, or features of nutrient deficiency. Participants with lactose intolerance. Participants with a history of substance addiction, including alcohol dependence, tobacco use in smoked or smokeless forms, Mava consumption, or abuse of psychoactive substances such as opioids, cannabinoids, sedatives, or stimulants within the past six months. Pregnant and lactating women. Participants currently receiving oral nutritional supplements will be excluded. Those who discontinue such supplements may be enrolled after completion of a two week washout period.

Design outcomes

Primary

MeasureTime frame
Improvement in signs and symptoms of Karshya. Improvement in weight, BMI, anthropometric measurements, and body fat composition. Improvement in IFN Gamma in adult Karshya individual. Timepoint: 90 Days

Secondary

MeasureTime frame
Improvement in Agnibala. Improvement in Quality of life using the WHOQOL BREF. Improvement in psychological well being GHQ 12 ScoresTimepoint: 90 days

Countries

India

Contacts

Public ContactDr Shalinee Kumari Mishra

Institute of Research and teaching in Ayurveda, Jamnagar

drshalinee@itra.edu.in9664540469

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026