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A Study Comparing Two Bone Graft Materials for Regenerating Bone Lost Around Teeth Due to Gum Disease.

Comparative Evaluation of the Effectiveness of Deproteinized Bovine Bone Material and Hydroxyapatite Crystal Collagen Fibers with A-PRF+ membrane in the Regeneration of Human Periodontal Infrabony Defects A Randomized Controlled Clinical Trial. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/114200
Enrollment
20
Registered
2026-07-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Deproteinized Bovine Bone Material with A-PRF + membrane: Under all aseptic condition and precautions, Under LA crevicular incision will be given followed by reflection of full thicknes

Sponsors

Datta Meghe Institute of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Presence of at least 1 or 2 radiographically detectable interproximal infrabony osseous defect with probing pocket depth less than or equal to 5 mm and clinical attachment loss less than or equal to 5 mm following initial therapy. 2)Depth of intraosseous component of the defect less than or equal to 3 mm by clinical and radiographic means, which will be confirmed on intra-surgical measurement. 3)A radiographic base of the defect at least 3 mm coronal to the apex of the tooth. 4)Presence of at least 3 mm width of keratinized gingiva around test teeth to allow complete soft tissue coverage of the defect

Exclusion criteria

Exclusion criteria: 1)Evidence of localized aggressive periodontitis. 2)Patients with unacceptable oral hygiene (Plaque Index greater than 1) 3)Smokers (recent history of smoking more than 10 cigarettes /day) or who used any of tobacco products. 4)Study tooth with inadequate endodontic / restorative treatments. 5)Study tooth with mobility exceeding grade II and exhibiting a class III or class IV furcation defect. 6)History of periodontal surgical therapy of the selected quadrant. 7)Pregnant females or lactating mothers

Design outcomes

Primary

MeasureTime frame
Radiographic Bone Fill in Infrabony defects at 6 months post surgery.Timepoint: Baseline and 6 months

Secondary

MeasureTime frame
1)Gain in Clinical Attachment Level (CAL) 2)Reduction in Probing Pocket DepthTimepoint: Baseline and 6 months

Countries

India

Contacts

Public ContactDr Priyanka Jaiswal

Datta Meghe Institue of Higher Education and Research

Priyanka.jaiswal@dmiher.edu.in9960713010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026