None listed
Conditions
Interventions
None listed
Sponsors
Institute of Teaching and Research in Ayurveda, Jamnagar
Eligibility
Inclusion criteria
Inclusion criteria: Age between 18 Years to 40 years. Apparently healthy individuals. Individual Yogya and willing for Virechana Karma. Person having Madhyama Koshta.
Exclusion criteria
Exclusion criteria: Person who is Ayogya and not willing for Virechana Karma. Pregnant and lactating women. Person having Mridu and Krura Koshta. Person having any other systemic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical evaluation confirming the purgative activity of the selected drugs and indicating a significant association with serotonin 5-hydroxytryptamine, 5-HT levels.Timepoint: 0th day, Before and after intervention, After Samsarjana Krama. | — |
Secondary
| Measure | Time frame |
|---|---|
| Identification of a defined set of bioactive phytochemicals with potential laxative activity from Terminalia chebula Retz, Cassia fistula Linn, Picrorhiza kurroa Royle ex Benth, and Operculina turpethum L. Silva Manso. Identification of predicted molecular interactions between the bioactive compounds of the selected drugs and serotonin 5-hydroxytryptamine, 5-HTrelated molecular targets using computational pharmacology approaches. Demonstration of a significant correlation between computational pharmacology findings and clinical outcomes, thereby establishing a mechanistic basis for the therapeutic action of the selected Adhobhaghara drugs used for Virechana Karma. Timepoint: 0th day, Before and after intervention, After Samsarjana Krama. | — |
Countries
India
Contacts
Public ContactDr NEHA G TANK
ITRA Jamnagar
Outcome results
None listed