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A study to evaluate whether an ultrasound guided left stellate ganglion block given before cardiac surgery can prevent early abnormal heart rhythms after surgery in high risk patient

Assessing the Impact of Pre-emptive Ultrasound-Guided Left Stellate Ganglion Block for Prevention of Early Postoperative Atrial and Ventricular Arrhythmias in High-Risk but Hemodynamically Stable Cardiac Surgery Patients: A Prospective Controlled Study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/114172
Enrollment
64
Registered
2026-07-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I518- Other ill-defined heart diseases Health Condition 2: I519- Heart disease, unspecified

Interventions

Intervention1: Pre emptive Ultrasound Guided Left Stellate Ganglion Block: Patients randomized to the intervention arm will receive an ultrasound-guided left stellate ganglion block after induction of

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. High-risk but hemodynamically stable adult patients undergoing elective on-pump cardiac surgery. 2. Sinus rhythm before surgery. 3. Elective mitral valve surgery with or without tricuspid valve surgery, combined CABG with valve surgery, or selected aortic valve surgery. 4. Presence of at least two of the following arrhythmia risk factors: a. Left atrial diameter 4.5 cm or more. b. Grade II or Grade III diastolic dysfunction. c. Left ventricular hypertrophy. d. Anticipated cardiopulmonary bypass time more than 120 minutes. 5. Left ventricular ejection fraction 40 percent or more. 6. Pulmonary artery systolic pressure 55 mmHg or less.

Exclusion criteria

Exclusion criteria: 1. Emergency cardiac surgery. 2. Permanent atrial fibrillation or heart block or presence of a permanent pacemaker or implantable cardioverter defibrillator. 3. Known allergy to local anaesthetics. 4. Local infection at the injection site. 5. Pre existing Horner syndrome or phrenic nerve palsy. 6. Coagulopathy with INR more than 1.5 or platelet count less than 50000 per mm3 before block placement.

Design outcomes

Primary

MeasureTime frame
Incidence of new-onset atrial or ventricular arrhythmias AF, atrial flutter, atrial tachycardia, non-sustained VT, sustained VT postoperatively Timepoint: 72 hours—

Secondary

MeasureTime frame
Total arrhythmia burden number and cumulative durationTimepoint: 72 hours;Time to first arrhythmic eventTimepoint: 72 hours;Need for rescue anti-arrhythmic drugs or cardioversionTimepoint: 72 hours;Vasopressor inotrope score in first 24 hoursTimepoint: 24 hours;Icu length of stayTimepoint: ICU DISCHARGE;adverse effects related to Stellate Ganglion blockTimepoint:—

Countries

India

Contacts

Public ContactDR KULBHUSHAN SAINI

PGIMER

kulbhushansaini007@gmail.com9968856948

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026