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To compare the effect of nebulised dexmedetomidine vs nebulised fentanyl on laryngoscopy to intubation in planned surgery under general anaesthesia: a prospective randomized double blinded placebo control study.

To compare the effect of nebulised dexmedetomidine vs nebulised fentanyl on laryngoscopy to intubation in planned surgery under general anaesthesia: a prospective randomized double blinded placebo control study. - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/114138
Enrollment
105
Registered
2026-07-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration

Interventions

Intervention1: Nebulized Dexmedetomidine: To Diminish the Pressor Response we are giving nebulization of dexmedetomidine Route :- Nebulization Dose :- 1mcg/kg Control Intervention1: Nebulized Fentan

Sponsors

Dr Indraja Roy
Lead Sponsor
Dr Anjali Borkar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients willingness to participate in the study. 2. Male and female in the age group of 18 to 60 years 3. Patients undergoing general anaesthesia 4. ASA - I and II 5. Mallampatti classification - I and II

Exclusion criteria

Exclusion criteria: 1.Lack of valid informed written consent 2. Patient refusal 3.ASA grade III and IV 4.Mallampatti classification III and IV 5.Patient having history of allergy of used drugs 6.Upper airway edema 7.Intubation took longer than fifteen seconds were not included 8.BMI more than 30 kg per meter square 9.Chronic analgesic or drug abuse 10.Pregnant patients

Design outcomes

Primary

MeasureTime frame
Change in HR, SBP, DBP, MAP and SPO 2 in response to laryngoscopy and intubationTimepoint: 1min 2min 5min 10min

Secondary

MeasureTime frame
To look for any adverse effects after nebulization.Timepoint: 1min 2min 5min 10min

Countries

India

Contacts

Public ContactDr Anjali Borkar

Datta Meghe Medical College

anjaliborkar93@gmail.com8237641594

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026