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A study comparing the types of oral bacteria in children with and without congenital heart disease.

qPCR based comparative analysis of oral bacterial microbiome in congenital heart disease pediatric patients and healthy controls in the age group 4 to 14 years - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/07/114137
Enrollment
46
Registered
2026-07-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q249- Congenital malformation of heart,unspecified

Interventions

Intervention1: Nil: Nil

Sponsors

Dr Ankan Chaudhary
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children aged 4 to 14 years whose parents or guardians provide written informed consent to participate in the study. The study group includes children with a confirmed medical diagnosis of congenital heart disease. The control group includes systemically healthy children with no history of cardiac, metabolic, or chronic infectious diseases.

Exclusion criteria

Exclusion criteria: Children who have received antibiotic therapy or used antimicrobial mouth rinses within the last 3 months prior to sample collection. Children who have undergone professional periodontal scaling or root planing in the last 3 months. Children currently undergoing fixed orthodontic treatment. Children with other systemic conditions such as diabetes mellitus, juvenile arthritis, or immunodeficiencies. Children with severe physical or mental limitations that prevent adequate cooperation for non invasive sample collection. Presence of acute dents alveolar abscesses or draining sinuses at the time of examination.

Design outcomes

Primary

MeasureTime frame
To quantify the salivary levels of cariogenic pathogens streptococcus mutans and lactobacillus species between congenital heart disease paediatric patients and healthy controlsTimepoint: Baseline

Secondary

MeasureTime frame
To detect and quantify periodontal pathogens porphyromonas gingivalis fusobacterium nucleatum aggregatibacter actinomycetemcomitans and compare the cycle threshold valuesTimepoint: Baseline

Countries

India

Contacts

Public ContactDr Ankan Chaudhary

Inderprastha Dental College and Hospital

ritikaaahuja@yahoo.com9717308580

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026