Health Condition 1: N179- Acute kidney failure, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
Institute of Critical Care Medicine and Anesthesiology
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged more than 18 years admitted with sepsis as defined by the Sepsis 3 criteria
Exclusion criteria
Exclusion criteria: 1 Age younger than 18 years 2 Survival time of less than 24hours 3 Pregnancy 4 Suspected or confirmed obstructive renal failure and Known renal artery stenosis and Suspected intra abdominal hypertension 5 Additionally we will not include patients recovering from previously diagnosed aki at the time of inclusion 6 Those with chronic kidney disease with a basal creatinine clearance value of lower than 30 ml per min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Development of KDIGO Stage 3 Acute Kidney Injury within 7 days of ICU admission as predicted by 1 Renal Resistive Index 2 Semi quantitative Power Doppler Ultrasound score This will be evaluated in terms of 1 Area Under the Curve 2 Sensitivity and specificity 3 Optimal cut-off values Timepoint: Within 7 days of ICU admission | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Diagnostic performance of semi quantitative PDU score alone in predicting KDIGO Stage 3 AKI 2 Association of RRI and PDU score with clinical outcomes i Length of ICU stay ii Requirement of Renal Replacement Therapy iii 28 day mortality 3 Correlation between ultrasound parameters and severity of illness i Correlation of RRI and PDU score with clinical or laboratory variables 4 Comparison of RRI and PDU values between outcome groups i Survivors vs non survivors at 28 days ii RRT vs non RRT patients Timepoint: 28 days | — |
Countries
India
Contacts
Public ContactDr Supriyo Sarkar
Medanta The Medicity Gurgaon
Outcome results
None listed