Health Condition 1: S063- Focal traumatic brain injury Health Condition 2: S066- Traumatic subarachnoid hemorrhage Health Condition 3: S065- Traumatic subdural hemorrhage Health Condition 4: S062- Diffuse traumatic brain injury Health Condition 5: S061- Traumatic cerebral edema
Conditions
Interventions
Intervention1: Stellate ganglion block: Unilateral stellate gangion block using drug 8 mL of 0.25% bupivacaine preservstive free, administered using a sonoplex nerve block needle 10cm using real time
Sponsors
Pradeep Daniel Katumalla
Eligibility
Inclusion criteria
Inclusion criteria: Patients who present within 48 hours of injury with a GCS score of 4 to 12
Exclusion criteria
Exclusion criteria: Brain stem injury GCS of 3 or 2T and or Fixed dialated pupils at admission GCS on arrival to TICU is more than or equal to 13 Anisochoria Neck soft tissue injury Cervical spine injuries are either clinically and radiologically proven Patient on cervical collar With the history of cerebrovascular disease or other brain disorders Basal skull fracture combined with evidence of cerebrospinal fluid leakage Pregnant or lactating women Polytrauma with shock and hypotension at presentation Any contraindication to regional analgesia, coagulopathy, Platelet count less than 50,000 and INR greater than 1.5 Poor or absent scanning window on transcranial doppler
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Middle Cerebral Artery Flow Velocity Vm-MCA on affected and unaffected sidesTimepoint: baseline ,15, 30, and 60 minutes, then at 2, 6, and 12 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Anteriror, middle and posterior y cerebral artery Peak flow velocity Mean flow velocityTimepoint: 15 minutes , 30 minutes , 1 hour , 2 hours , 6 hours , 24 hours , 48 hours , 72 hours;EEG Patient state index, Spectral Edge frequencyTimepoint: 15 minutes , 30 minutes , 1 hour , 2 hours , 6 hours , 24 hours , 48 hours , 72 hours;Blood pressure and blood pressure variabilityTimepoint: 24 hours , 48 hours , 72 hours;Cam ICU Delerium and Richmond agitation sedation scoreTimepoint: 24 hours , 48 hours , 72 hours;Glasgow outcome scale extendedTimepoint: at discharge | — |
Countries
India
Contacts
Public ContactPradeep Daniel
AIIMS Raipur
Outcome results
None listed