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A study to compare the effectiveness of Excimer laser with Tacrolimus ointment versus Tacrolimus ointment alone in treatment of stable vitiligo.

Comparison of efficacy between Combined excimer laser and topical tacrolimus VS Topical tacrolimus in Vitiligo- A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113997
Enrollment
92
Registered
2026-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80- Vitiligo

Interventions

Intervention1: Excimer Laser: Therapeutic, 308nm Excimer Laser Intervention2: Excimer laser and topical Tacrolimus: This study aims to compare the efficacy of 308 nm excimer laser therapy combined wit

Sponsors

Aiims Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients from 3 to 60 years of either sex attending the OPD of the Department of Dermatology at AIIMs Patna and clinically diagnosed as case of non-segmental vitiligo with stable disease that is no new lesions or progression of existing lesions for past 1year with VIDA 0. Patients with lesions located on the face, neck, trunk, or limbs, excluding acral and mucosal areas. Patients willing to provide written informed consent and comply with study protocol and follow up visits.

Exclusion criteria

Exclusion criteria: Segmental vitiligo or universal vitiligo. Patients who have received systemic immunosuppressants, phototherapy, or topical treatment for vitiligo in the past 4 weeks. Patients with photosensitive dermatoses, history of keloids, or any active skin infections over vitiligo lesions. Pregnant or lactating women and children less than or equal to 2years. Patients with uncontrolled systemic illnesses or known hypersensitivity to tacrolimus.

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of 308 nm excimer laser combined with topical tacrolimus versus topical tacrolimus monotherapy in achieving repigmentation within 12 weeks, assessed using the Physicians Global Assessment scale, in patients with nonsegmental and stable vitiligo.Timepoint: 12 weeks—

Secondary

MeasureTime frame
To compare patient satisfaction and quality of life outcomes between the two groups using a standardized assessment tool which is Dermatology Life Quality Index. To explore variations in treatment response based on lesion site, duration, and skin type.Timepoint: 12 weeks—

Countries

India

Contacts

Public ContactDr Soumya Sulagna Mahapatra

AIIMS Patna

dr.swetalinapradhan@gmail.com7978843633

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026