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The need of a drug given before inducing to decrease the anxiety and intubation response in the children undergoing General Anesthesia

Nebulized Dexmedetomidine vs Nebulized Midazolam: A Pediatric Premedication Perspective in General Anesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113987
Enrollment
50
Registered
2026-07-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R69- Illness, unspecified

Interventions

Intervention1: GROUP A: PATEINT RECEIVING NEBULIZED DEXMEDITOMEDINE 0.75-2 MICROGRAMS/KG 30 minutes before Intubation Control Intervention1: GROUP B: PATEINTS RECEIVING NEBULIZED NEBULIZED MIDAZOLAM 0

Sponsors

DR Tejaswini K M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age:5-12 years American Society of Anesthesiologists Class I AND II Elective Surgery under General Anesthesia Mallampati Class I AND II

Exclusion criteria

Exclusion criteria: Refusal to participate in the study Mallampati Class III and IV Patient with Critical Illnesses Patient who is known case of Seizures and Congenital Abnormalities Allergy to Midazolam and Dexmedetomidine American Society of Anesthesiologists 3 and 4, Obesity grade 3 and 4 Respiratory Tract Infections Developmental Delay and Psychiatric Illnesses Emergency surgery

Design outcomes

Primary

MeasureTime frame
TO STUDY THE EFFICACY OF NEBULIZED DEXMEDITOMEDINE AND NEBULIZED MIDAZOLAM AS SEDATIVE PREDICATION FOR FACILITATING FACE MASK ACCEPTANCETimepoint: 0, 5 minute, 10 minute, 20 minute, 30 minutes and at the end of the surgery

Secondary

MeasureTime frame
To compare the effect of nebulized dexmedetomidine, midazolam as sedative premedication for facilitating face mask acceptance. To compare the hemodynamic stability during laryngoscopy. To study the other effects of the drugs on the hemodynamics and the homeostasis apart from the sedative, anti-anxiety and analgesic properties To assess the onset and duration of sedation. To compare any adverse effects associated with each drug. To compare the quality of the depth of analgesia and sedation given by nebulized midazolam and dexmedetomidine Timepoint: 0, 5 minute, 10 minute, 20 minute, 30 minutes and at the end of the surgery

Countries

India

Contacts

Public ContactDR Srinivas V Y

Mysore Medical College and Research Institute

drsrinivasvy@gmail.com9448165082

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026