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Enhancing Healing of Deep Gum and Bone Defects Using Laser Therapy and Natural Regenerative Materials

Effect of Low Level Laser Therapy with single flap approach using Titanium platelet rich fibrin in treatment of Intrabony periodontal defects - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/07/113962
Enrollment
36
Registered
2026-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: low level laser therapy: duration is for 6 monthsSingle Flap Approach will be performed to access the intrabony defect, followed by application of low level laser therapy followed by pl

Sponsors

Koduru Lakshmi Sudhanya
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects of age 25 55 years. 2. Probing depth of more than 6mm. 3. Subjects with 2 or 3 wall intrabony defect in the posterior teeth with radiographic evidence of vertical bone loss more than 3mm. 4. Subjects willing to participate in the study 5. Subjects with normal hematological count 6. Subjects with properly aligned tooth at the site of defect ..

Exclusion criteria

Exclusion criteria: 1. Pregnant women and lactating mothers. 2. Use of any form of tobacco. 3. Subjects with any systemic disease that contraindicate in periodontal surgery 4. Having history of drug usage that impact wound healing or platelet function such as anticoagulants, immunosuppressants . 5. Subjects who are under periodontal therapy from the past 6 months.

Design outcomes

Primary

MeasureTime frame
Clinical outcome - Wound healing index (WHI) Radiological outcome Intrabony defect depth (IBDD), Intrabony defect width (IBDW) Timepoint: at 1 week WHI at baseline and 6 months IBDD,IBDW

Secondary

MeasureTime frame
Clinical outcome - Plaque Index (PI), Gingival Index (GI), Probing Pocket depth (PPD), Clinical attachment level (CAL) Timepoint: Time points Baseline,3 months 6 months

Countries

India

Contacts

Public ContactLakshmi Sudhanya Koduru

Sibar institute of dental sciences

anumala.deepas@gmail.com9618501146

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 10, 2026